Blood Type/Blood group In this whole world all the people are born with a blood type which may be similar or dissimilar to someone. Blood type is classified on the basis of presence or absence of antigen (surface of RBC ) and antibody. Karl Landsteiner discovered ABO blood type in 1901 for which he was rewarded with novel prize in 1930. In 1940 Landsteiner and Alexander wiener discovered Rh factor( Rhesus factor). According to International society for blood transfusion(ISBT) till now 28 blood group system have been identified. What are Antigen and Antibody ? Normal human body contains 5 liters of blood volume in which 55% is composed of plasma and 45% is composed of blood cells( RBC, WBC,Platelets). Antigen are the protein molecules present in surface of RBC which have the capacity to stimulate antibodies. Antibodies are the protein found in plasma which helps in immune response. Types of antibodies( IgM, IgD, IgG,IgA,IgE). Blood type Antigen